Despite being a poorly understood brain region, the orbitofrontal cortex (OFC) generates much interest because of some of the roles it is speculated to play in higher-order cognition, such as decision-making. The prefrontal cortex and frontal lobes are believed to be necessary for reasoning, logical thought, and personality.

The orbitofrontal cortex is a very complicated part of our brain. This article will discuss what the orbitofrontal cortex is, its functions, the consequences if it is damaged, the diagnosis and causes of damage, and treatment.

What Is An Orbitofrontal Cortex?Orbitofrontal Cortex - Cognition And BehaviorWhat Causes Damage To The Orbitofrontal Cortex?How To Diagnose Orbitofrontal Cortex Damage?What Happens If The Orbitofrontal Cortex Is Damaged?How To Treat Orbitofrontal Cortex Damage?Coping With A Loved One With Orbitofrontal Cortex DamageConclusion

What Is An Orbitofrontal Cortex?

Orbitofrontal Cortex - Cognition And Behavior

What Causes Damage To The Orbitofrontal Cortex?

How To Diagnose Orbitofrontal Cortex Damage?

What Happens If The Orbitofrontal Cortex Is Damaged?

How To Treat Orbitofrontal Cortex Damage?

Coping With A Loved One With Orbitofrontal Cortex Damage

Conclusion

The orbitofrontal cortex (OFC) is located directly above the eye sockets in the front part of the brain. It connects to the brain’s sensory regions, memory, and emotion centers. The orbitofrontal cortex is crucial in how we interact with the world.

Consequently, when damaged, it can result in severe problems. The exact function of the orbitofrontal cortex is still only partially understood.

Neuroscientists have ascribed many functions to this region based on the behavior of individuals with frontal lobe damage. Among the cognitive functions usually associated with the orbitofrontal cortex are the following:

The orbitofrontal cortex (OFC) is important for behavior and frequently suffers damage from various injuries, including closed head trauma, cerebrovascular accidents, malignancies, and neurosurgical procedures.

People with injury to the OFC appear to remain cognitively intact regardless of the (severe) behavioral alterations that result from OFC injuries, at least when evaluated using common neuropsychological measures. Neuropsychological tests that examine reversal learning, social cognition, and gambling in these patients reveal a deterioration.

This review aims to establish a causal relationship between these recent neuropsychological test results and behavior.

The findings imply that behavioral disinhibition and impaired perception of expressive emotion are more frequently related to socially unacceptable behavior in patients with orbitofrontal lesions. The theory of mind test (the faux pas test) does not seem responsive to orbitofrontal lesions.

Future research should include a greater number of patients with well-defined sites in the OFC to better understand the role of the OFC in cognition and behavior. It should integrate quantitative behavioral measurements and specialized neuropsychological tests.

Brain Tumors

When abnormal cells develop within the brain, they produce a brain tumor. Tumors are classified into benign (non-cancerous) and malignant (cancerous) tumors.

These are further subdivided into primary tumors, which begin inside the brain, and secondary tumors, which usually spread from cancers outside the brain (metastasis tumors). Symptoms of all forms of brain tumors vary according to the size of the tumor and the portion of the brain affected.

Headaches, seizures, eye problems, vomiting, and mental abnormalities are all possible symptoms. Additional symptoms may include difficulties walking, speaking, experiencing sensations, or becoming unconscious.

Cerebral Palsy

Dementia

Dementia is a word used to describe illnesses that result in memory loss and other cognitive difficulties. Frontotemporal dementia (FTD) is a collection of frontal and temporal lobe abnormalities.

FTD is the second most prevalent cause of dementia among individuals under 65. Typically, people with FTD exhibit altered behavior and personality. They could also have language difficulties. They could also have language difficulties. Sometimes, this kind of Alzheimer’s disease is mistaken as FTD.

Huntington’s Disease

Huntington’s disease (HD), (also called Huntington’s chorea), is a hereditary neurological disease. The first indications are frequently minor changes in mood or mental ability.

A general loss of coordination and an unstable walk is usually the result. It is also a basal ganglia condition that causes chorea, a hyperkinetic movement disorder.   Chorea, or uncoordinated, uncontrollable body motions, becomes more noticeable as the condition progresses.

Physical abilities deteriorate gradually until coordinated movement becomes impossible and the patient cannot speak. As people age, their mental capacities deteriorate and result in dementia.

Parkinson’s Disease

Parkinson’s disease (PD), often known as Parkinson’s disease, is a chronic degenerative condition of the central nervous system that primarily affects the motor system.

Non-motor symptoms normally appear gradually, and as the disease progresses, they become more common. Tremor, slow movement, rigidity, and trouble walking are the most noticeable early symptoms.

Many patients with Parkinson’s disease experience despair, anxiety, and apathy, which can lead to cognitive and behavioral issues. Parkinson’s disease dementia becomes prevalent as the condition progresses. Parkinson’s patients could also experience issues with their sensory systems and sleeping patterns.

Stroke

When the blood supply to the frontal lobe is disrupted, this brain region loses function. This could occur as a result of a brain hemorrhage.

Vascular dementia can develop after several minor strokes. This is the most prevalent cause of frontal lobe dysfunction. Vascular dementia has been associated with Alzheimer’s disease and other neurodegenerative conditions.

Diagnostic scans help medical professionals identify frontal lobe infections and strokes. Computed tomography (CT or CAT) and magnetic resonance imaging (MRI) are possibilities. An MRI produces a 2- or 3-dimensional image of the brain using radio waves and a magnetic field.

A CT scan combines many X-rays to produce a 3D image. On a scan, some causes, such as a traumatic brain injury or dementia, may show up as atrophy or loss of brain tissue. The scan could come up blank. Both MRI and CT scans are reliable methods for vascular dementia diagnosis.

A healthcare professional can determine frontal lobe injury with a thorough neuropsychological assessment or a concussion test. These exams examine:

The following behavioral abnormalities may be seen in someone who has suffered damage to their orbitofrontal cortex.

Character Changes

Finally, personality changes might result from damage to the orbitofrontal cortex. The mid-1800s instance of Phineas Gage led to the discovery of the link between frontal lobe injury and personality change.

When Gage, a railroad worker, was tamping explosives into a drill hole in 1848, the powder unintentionally exploded. The iron rod shot through Gage’s left cheek, into his orbitofrontal brain, and out the top of his skull due to the explosion.

Although Gage managed to survive the original injuries, the profound personality shift that followed led his friends to refer to him as “no longer Gage.” Many family members note that their loved ones seem somewhat “different” after their accident, even though most TBI patients don’t undergo the kind of drastic personality change that Gage did.

Impetuous Action

One of the main signs of orbitofrontal injury is a decrease in impulse control. People who experience this symptom will act improperly.

For instance, they might say offensive things or divulge personal information too readily. They might even start acting violently. Additionally, impulsivity may lead them to behave recklessly and engage in risky, life-threatening activities.

Reduced Emotional Reactions

Damage to the OFC may alter how the body reacts to emotions, leading to impulsivity and bad judgment. For instance, when making a bold decision, healthy patients exhibit physical symptoms of worry, such as sweaty palms. Patients with injury to the orbitofrontal cortex, however, did not.

Additionally, healthy patients made less dangerous, more rational decisions. This shows that signals from the orbitofrontal cortex help people recognize if they’re about to make a bad judgment. As a result, if it is injured, the person cannot get a warning before acting, which may result in unsafe decisions.

Poor Judgement

The orbitofrontal cortex also assists decision-making based on the relative merits of several options. However, the orbitofrontal cortex might be involved in more complex judgments than simple ones. According to recent studies, the OFC aids in forecasting decisions based on experience.

The individual is considered to have an orbital personality and may be diagnosed with acquired ASPD (antisocial personality disorder) if their actions hurt others. Since most orbitofrontal individuals can behave better, this condition is uncommon.

Furthermore, not all behavioral changes are unfavorable. Some people find that their injury makes them happier and more animated. This fact exemplifies how unpredictable the signs of a brain injury may be.

Depending on the etiology, several treatments are used for frontal lobe damage. For instance, antibiotics can be used to treat an infection. Radiation, chemotherapy, or surgery are all options for treating brain tumors.

Degenerative illnesses like dementia, Huntington’s disease, and Parkinson’s disease currently have no known cures. Symptoms can be improved with medication and way of life adjustments. Treatment of orbitofrontal cortex damage includes;

Rehabilitation

Cognitive Behavioral Therapy (CBT)

Rehabilitation for frontal lobe damage-related cognitive and interpersonal issues can be challenging. Therapy that assists clients in controlling their emotions and reining impulsive conduct might be beneficial.

One of the most challenging post-concussive complications for family and friends to deal with is orbitofrontal damage. The person they once knew and loved may appear drastically different from how they once were.

To help you cope with the behavior and personality changes of a loved one with orbitofrontal cortex damage, the following tips can be of assistance;

Keep in mindthat they don’t have ultimate control. Remember that your loved ones may not be fully in control when they say anything hurtful. The person you love is still there, but they are far more emotional and expressive than they once were.

Establish limits.You should kindly but firmly correct them if they act impolitely or inappropriately. Calmly explain and ensure they understand they can’t continue to act in such a way while doing your best to avoid embarrassing them.

Sometimes imaging scans can be used to identify frontal lobe injury. A neuropsychological assessment might be required in other circumstances. Medication, rehabilitation, surgery, or counseling are possible treatments for orbitofrontal cortex damage.

References

Know Your Brain: Orbitofrontal Cortex (neuroscientificallychallenged.com)

Frontal Lobe Damage: Symptoms, Cause, Diagnosis, Treatment (verywellhealth.com)

Stimulating Brain Area May Ease Tough Depression (webmd.com)

Related posts:Motor Cortex FunctionParts Of The Brain (FULL Outline)Prefrontal Cortex FunctionCerebral Cortex (Location, Function, Images)Where is the Primary Visual Cortex Located?

Reference this article:Practical Psychology. (2022, July).Orbitofrontal Cortex.Retrieved from https://practicalpie.com/orbitofrontal-cortex/.Practical Psychology. (2022, July). Orbitofrontal Cortex. Retrieved from https://practicalpie.com/orbitofrontal-cortex/.Copy

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Practical Psychology. (2022, July).Orbitofrontal Cortex.Retrieved from https://practicalpie.com/orbitofrontal-cortex/.Practical Psychology. (2022, July). Orbitofrontal Cortex. Retrieved from https://practicalpie.com/orbitofrontal-cortex/.Copy

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